Harold and Kumar are on a quest to satisfy their cravings for burgers and find themselves on a hilarious all-night adventure as they run into one screwy obstacle after another.

Jesse and Chester are two bumbling stoners who wake up one morning from a night of partying and cannot remember where they parked their car. This prompts them on a journey to find it. Along the way, they encounter a variety of people who include their angry girlfriends Wilma and Wanda, whose house they trashed, an angry street gang, a transexual stripper hounding them for a suitcase full of stolen money, a cult of alien seeking fanatics, and a group...