An assassination attempt is made on the life of the president by a teleporting mutant. This act upsets the entire world and entices the president to begin the mutant-human war as predicted by Charles Xavier earlier. In an effort to get to the bottom of the attack and prevent world-wide war, Xavier sends out Storm and Dr. Jean Grey to search for the teleporting mutant and discover the truth behind the assassination attempt.

Beck is anxious to retire from his bounty hunter work, but his boss, Walker, has one more "retrieval" job for him. He sends Beck into the Brazilian rainforest to bring back his wayward son, Travis. Travis is there looking for a gold statue, which he could sell for millions if he finds it. The powerful Hatcher owns the area's huge mine, and feels that anything found in the area is his property. He refuses to let Beck take Travis back to the U.S. until...

After the re-emergence of the world's first mutant, world-destroyer Apocalypse, the X-Men must unite to defeat his extinction level plan.

Following a shocking attack on the President, the X-men must stand united with their deadliest enemies to combat a menace that threatens every mutant on the planet, and possibly all of mankind.